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V-100型小動物呼吸機是玉研儀器專門為小型實驗動物(小鼠、大鼠、豚鼠等)而進行自主研發(fā)設(shè)計的高性能、高精度呼吸機,具有控制準確、方便實用、性能穩(wěn)定的特點。呼吸參數(shù)(呼吸頻率,呼吸比,潮氣量,氣道壓力)實時數(shù)字顯示,觀察直觀。
V-100型小動物呼吸機采用定容和定壓式控制,可以保證動物充足的通氣。潮氣量調(diào)節(jié)范圍 0~10ml,呼吸頻率調(diào)節(jié)范圍 1~300 次/分,適用于需要微小氣量的小動物,如小鼠、大鼠、豚鼠、倉鼠等。
V-100采用定容型正壓呼吸,工作時預(yù)設(shè)通氣量,呼吸機送氣達預(yù)設(shè)容積后停止送氣,依靠肺胸的彈性回縮力被動呼氣。采用定容型通氣模式可以保證每次給動物通入相同體積的氣體,滿足動物充足的通氣。內(nèi)置進口長壽命的氣泵,保證輸出的氣體流量穩(wěn)定精確。呼吸機根據(jù)設(shè)置的參數(shù)有節(jié)律地輸出氣流,經(jīng)吸氣管進入動物肺內(nèi),使肺擴張以達到氣體交換的目的。定壓式控制模式下,通過設(shè)定氣道壓力,氣流進行簡單地調(diào)整,實際呼吸參數(shù)顯示在液晶顯示屏上。壓力模式以及容量模式通過開關(guān)進行切換。 在任何模式下,可以通過設(shè)置嘆息功能來進行自動嘆息。
產(chǎn)品主要特點:
1. 適用于大小鼠、豚鼠、家兔等小型實驗動物;
2. 電動電控呼吸機,無須使用高壓氣源;
3. 通氣模式:間歇性正壓通氣、持續(xù)性正壓通氣、定容通氣、定壓通氣、自動嘆息通氣;
4. 大小鼠呼吸通路,低死腔,穩(wěn)定潮氣量輸出;
5. 配小鼠、大鼠兩種氣管插管,可從口部無創(chuàng)插入進行輔助呼吸;
6. 工作過程隨時改變設(shè)定參數(shù),立即生效,無需停止運行進行設(shè)定;
7. 觸摸薄膜按鍵控制,使用便捷人性化;
8. 可搭配氣體麻醉機組成麻醉呼吸系統(tǒng);
9. 呼吸頻率調(diào)節(jié)范圍:1-200 次/分;
10. ***小潮氣量輸出100uL,步進100uL,上限不低于10mL;
11. 數(shù)字式顯示直觀清晰,潮氣量、呼吸壓力、吸呼比等參數(shù)實時顯示;
12. 呼吸比:1:5~5:1,步進 0.1,任意設(shè)定,多達上千種吸呼比;
型號:V-100
參考文獻:
1.Sun, Zhenxing et al. “Myocardium-targeted transplantation of PHD2 shRNA-modified bone mesenchymal stem cells through ultrasound-targeted microbubble destruction protects the heart from acute myocardial infarction.” Theranostics vol. 10,11 4967-4982. 6 Apr. 2020, doi:10.7150/thno.43233
2.Zhang, Li et al. “Localized Delivery of shRNA against PHD2 Protects the Heart from Acute Myocardial Infarction through Ultrasound-Targeted Cationic Microbubble Destruction.” Theranostics vol. 7,1 51-66. 1 Jan. 2017, doi:10.7150/thn.16074
3.Cai, Heng et al. “Mild Hypothermia Promotes Ischemic Tolerance and Survival of Neural Stem Cell Grafts by Enhancing Global SUMOylation.” Oxidative medicine and cellular longevity vol. 2022 6503504. 27 May. 2022, doi:10.1155/2022/6503504
4.Zhang, Xuerui et al. “Dominant Negative FADD/MORT1 Inhibits the Development of Intestinal Intraepithelial Lymphocytes With a Marked Defect on CD8αα+TCRγδ+ T Cells.” Frontiers in immunology vol. 9 2038. 10 Sep. 2018, doi:10.3389/fimmu.2018.02038
5.Ma, HaiXiang et al. “Dorsal raphe nucleus to pre-B?tzinger complex serotonergic neural circuit is involved in seizure-induced respiratory arrest.” iScience vol. 25,10 105228. 27 Sep. 2022, doi:10.1016/j.isci.2022.105228
6.Ren, Wenbo et al. “Moderate hypothermia induces protein SUMOylation in bone marrow stromal cells and enhances their tolerance to hypoxia.” Molecular medicine reports vol. 16,5 (2017): 7006-7012. doi:10.3892/mmr.2017.7425
7.Zhang, X-G et al. “Investigating the expression of miRNA-133 in animal models of myocardial infarction and its effect on cardiac function.” European review for medical and pharmacological sciences vol. 23,13 (2019): 5934-5940. doi:10.26355/eurrev_201907_18338
8.Wang, Juntao et al. “Protective effects of dexmedetomidine on lung in rats with one-lung ventilation.” Experimental and therapeutic medicine vol. 17,1 (2019): 187-192. doi:10.3892/etm.2018.6952
9.Qing, Hua et al. “Regulation of adventitial interstitial fluid circulation by heartbeat and respiration.” bioRxiv doi:10.1101/2022.10.18.512678
10.韓悅, 刁玉剛, 宋丹丹, 等. 無血預(yù)充大鼠體外循環(huán)心臟不停跳模型的改進[J]. 中國體外循環(huán)雜志, 2020.
V-100型小動物呼吸機是玉研儀器專門為小型實驗動物(小鼠、大鼠、豚鼠等)而進行自主研發(fā)設(shè)計的高性能、高精度呼吸機,具有控制準確、方便實用、性能穩(wěn)定的特點。呼吸參數(shù)(呼吸頻率,呼吸比,潮氣量,氣道壓力)實時數(shù)字顯示,觀察直觀。
V-100型小動物呼吸機采用定容和定壓式控制,可以保證動物充足的通氣。潮氣量調(diào)節(jié)范圍 0~10ml,呼吸頻率調(diào)節(jié)范圍 1~300 次/分,適用于需要微小氣量的小動物,如小鼠、大鼠、豚鼠、倉鼠等。
V-100采用定容型正壓呼吸,工作時預(yù)設(shè)通氣量,呼吸機送氣達預(yù)設(shè)容積后停止送氣,依靠肺胸的彈性回縮力被動呼氣。采用定容型通氣模式可以保證每次給動物通入相同體積的氣體,滿足動物充足的通氣。內(nèi)置進口長壽命的氣泵,保證輸出的氣體流量穩(wěn)定精確。呼吸機根據(jù)設(shè)置的參數(shù)有節(jié)律地輸出氣流,經(jīng)吸氣管進入動物肺內(nèi),使肺擴張以達到氣體交換的目的。定壓式控制模式下,通過設(shè)定氣道壓力,氣流進行簡單地調(diào)整,實際呼吸參數(shù)顯示在液晶顯示屏上。壓力模式以及容量模式通過開關(guān)進行切換。 在任何模式下,可以通過設(shè)置嘆息功能來進行自動嘆息。
產(chǎn)品主要特點:
1. 適用于大小鼠、豚鼠、家兔等小型實驗動物;
2. 電動電控呼吸機,無須使用高壓氣源;
3. 通氣模式:間歇性正壓通氣、持續(xù)性正壓通氣、定容通氣、定壓通氣、自動嘆息通氣;
4. 大小鼠呼吸通路,低死腔,穩(wěn)定潮氣量輸出;
5. 配小鼠、大鼠兩種氣管插管,可從口部無創(chuàng)插入進行輔助呼吸;
6. 工作過程隨時改變設(shè)定參數(shù),立即生效,無需停止運行進行設(shè)定;
7. 觸摸薄膜按鍵控制,使用便捷人性化;
8. 可搭配氣體麻醉機組成麻醉呼吸系統(tǒng);
9. 呼吸頻率調(diào)節(jié)范圍:1-200 次/分;
10. ***小潮氣量輸出100uL,步進100uL,上限不低于10mL;
11. 數(shù)字式顯示直觀清晰,潮氣量、呼吸壓力、吸呼比等參數(shù)實時顯示;
12. 呼吸比:1:5~5:1,步進 0.1,任意設(shè)定,多達上千種吸呼比;
型號:V-100
參考文獻:
1.Sun, Zhenxing et al. “Myocardium-targeted transplantation of PHD2 shRNA-modified bone mesenchymal stem cells through ultrasound-targeted microbubble destruction protects the heart from acute myocardial infarction.” Theranostics vol. 10,11 4967-4982. 6 Apr. 2020, doi:10.7150/thno.43233
2.Zhang, Li et al. “Localized Delivery of shRNA against PHD2 Protects the Heart from Acute Myocardial Infarction through Ultrasound-Targeted Cationic Microbubble Destruction.” Theranostics vol. 7,1 51-66. 1 Jan. 2017, doi:10.7150/thn.16074
3.Cai, Heng et al. “Mild Hypothermia Promotes Ischemic Tolerance and Survival of Neural Stem Cell Grafts by Enhancing Global SUMOylation.” Oxidative medicine and cellular longevity vol. 2022 6503504. 27 May. 2022, doi:10.1155/2022/6503504
4.Zhang, Xuerui et al. “Dominant Negative FADD/MORT1 Inhibits the Development of Intestinal Intraepithelial Lymphocytes With a Marked Defect on CD8αα+TCRγδ+ T Cells.” Frontiers in immunology vol. 9 2038. 10 Sep. 2018, doi:10.3389/fimmu.2018.02038
5.Ma, HaiXiang et al. “Dorsal raphe nucleus to pre-B?tzinger complex serotonergic neural circuit is involved in seizure-induced respiratory arrest.” iScience vol. 25,10 105228. 27 Sep. 2022, doi:10.1016/j.isci.2022.105228
6.Ren, Wenbo et al. “Moderate hypothermia induces protein SUMOylation in bone marrow stromal cells and enhances their tolerance to hypoxia.” Molecular medicine reports vol. 16,5 (2017): 7006-7012. doi:10.3892/mmr.2017.7425
7.Zhang, X-G et al. “Investigating the expression of miRNA-133 in animal models of myocardial infarction and its effect on cardiac function.” European review for medical and pharmacological sciences vol. 23,13 (2019): 5934-5940. doi:10.26355/eurrev_201907_18338
8.Wang, Juntao et al. “Protective effects of dexmedetomidine on lung in rats with one-lung ventilation.” Experimental and therapeutic medicine vol. 17,1 (2019): 187-192. doi:10.3892/etm.2018.6952
9.Qing, Hua et al. “Regulation of adventitial interstitial fluid circulation by heartbeat and respiration.” bioRxiv doi:10.1101/2022.10.18.512678
10.韓悅, 刁玉剛, 宋丹丹, 等. 無血預(yù)充大鼠體外循環(huán)心臟不停跳模型的改進[J]. 中國體外循環(huán)雜志, 2020.